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Cruises from San Diego

Scroll down for our most popular recommended cruises and to view the full list of cruises from San Diego to Mexico, Panama, Hawaii and beyond. Only cruises with remaining available cabins are listed. If you cannot find your ideal cruise from San Diego, you may wish to try cruises from San Francisco or cruises from Los Angeles for more options.

Our cruise specialists are on hand to help you with all your enquiries on cruises from San Diego. Contact us or request a call back to chat with one of our friendly consultants. Don’t forget to ask about our fantastic flight and hotel deals to package up your American holiday.